Immune complex-induced inhibition of osteoclastogenesis is mediated via activating but not inhibitory Fcγ receptors on myeloid precursor cells

Lilyanne C Grevers,J Sjef Verbeek,Vincent Everts,Peter L E M Van Lent,Teun J De Vries,Wim B Van Den Berg

doi:10.1136/annrheumdis-2012-201568

Immune complex-induced inhibition of osteoclastogenesis is mediated via activating but not inhibitory Fcγ receptors on myeloid precursor cells

Lilyanne C Grevers, J Sjef Verbeek + Show 4 more

https://doi.org/10.1136/annrheumdis-2012-201568

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Journal: Annals of the Rheumatic Diseases	Publication Date: Aug 23, 2012
Citations: 38

Affiliation: Radboud University Nijmegen, Radboud University Nijmegen Medical Centre, Leiden University Medical Center, Academic Center for Dentistry Amsterdam, University of Amsterdam

#Immune Complexes #Presence Of Proinflammatory Mediators + Show 8 more

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ObjectiveTo investigate the role of Fcγ receptors (FcγRs) in osteoclastogenesis and osteoclast function.MethodsBone destruction was analysed in arthritic knee joints of several FcγR-knockout mouse strains. Unfractionated bone marrow cells were...

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