Abstract
Acute and chronic serum sickness was induced in rabbits by subcutaneous and intravenous innoculation of bovine serum albumin (BSA). Immunofluorescent microscopic observation of their eyes revealed the presence of granular deposits of rabbit IgG and C 3 and of BSA in the ciliary process. These pathological findings were comparable to those observed in the choroid plexus and renal glomeruli. Our experimental systemic serum sickness model in rabbits may prove useful in more fully understanding the uveitis associated with the collagen vascular diseases, sarcoidosis, Crohn's disease and malignancy.
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