Abstract
Meeting abstracts Cancer vaccines attracted a lot of attention as an alternative/adjuvant therapeutic approach for patients with advanced metastatic cancer. Preclinical studies showed that tumors can evade the adaptive immune response by activation of immune checkpoints in the tumor micro-
Highlights
Cancer vaccines attracted a lot of attention as an alternative/adjuvant therapeutic approach for patients with advanced metastatic cancer
Preclinical studies showed that tumors can evade the adaptive immune response by activation of immune checkpoints in the tumor microenvironment
Thirty three tumor/normal pairs, including 7 MSIhigh samples have been analyzed for their immunologic environment, including lymphocytes subsets, cytokine production, immune checkpoint expression and myeloid populations
Summary
Immune checkpoints in MSI and CSI colorectal cancers and their translational implications Nicolás J Llosa*, Franck Housseau, Elizabeth Wick, Lizzy Hechenbleikner, Michael Cruise, Robert Anders, Cynthia Sears, Drew Pardoll. From Society for Immunotherapy of Cancer 28th Annual Meeting National Harbor, MD, USA. 8-10 November 2013
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