Abstract

Aspergillus niger NCIM 589 spores were immobilized on high density polyethylene (HDPE), using polyethyleneimine (PEI) as the surface coating with as high as 50% adsorption compared with 30% reported earlier. The adsorption time was reduced to 2 h from the earlier 24 h, and pretreatment with a solvent was eliminated. The biocatalyst could be used for 11α-hydroxylation of Progesterone to give better conversions than alginate-entrapped or free mycelia.

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