Abstract
Reconstruction of hard tissue continuity defects caused by ablative tumor surgery have been traditionally reconstructed with autogenous cancellous marrow grafts or microvascular free flaps. Although results have been predictable from both methods of reconstruction, the morbidity associated with bone harvest is quite significant for the patient. With the advances made in tissue engineering, successful and predictable results has been obtained with using a combination of 100% cadaver bone, Bone Marrow Aspirate Concentrate (BMAC) and rhBMP-2 for immediate reconstruction for benign tumor extirpations via extra-oral approach. In light of these successful outcomes the same combination was evaluated with an intraoral approach. This case study aims to evaluate the success of immediate mandibular reconstruction via intra-oral approach without any autogenous bone harvesting.
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