Immediate and short-term biventricular function assessment post-atrial septal defect surgical versus device closure: A comparative two-dimensional speckle tracking study

Abstract

BackgroundQuantitative assessment of biventricular function in atrial septal defect (ASD) patients before and after closure remains debatable. This study aimed to assess the global biventricular strain in ASD patients before and 24 h and one month after transcatheter and surgical closure. MethodsStandard Two-Dimensional (2D)-echocardiography and strain imaging were done for sixty ASD patients before, and 24 h and one month after correction by surgery or transcatheter intervention. Also, all echocardiographic and strain parameters for twenty age-matched controls were included. 2D- Strain (S) imaging was measured by speckle tracking analysis. ResultsRight ventricle global longitudinal systolic strain (RV GLSS) was significantly reduced after 24 h of ASD closure in both device and surgical groups. The reduction in RV GLSS was greater in the surgical group (8.00 ± 1.76% vs 2.60 ± 0.72%, P = 0.004). Left ventricle global longitudinal systolic strain (LV GLSS) showed a statistically significant decline after 24 h of device closure (from −24.47 ± 0.57% to −23.14 ± 0.65%, p = 0.048) followed by a significant increase in LV GLSS (from-23.14 ± 0.65% to −24.15 ± 0.75%, p = 0.038) after 1 month. ConclusionsThe ASD closure had a rapid impact on geometric and functional changes of both ventricles regardless of the way of closure. Interestingly, the rate of improvement in LV-GLSS was higher after device closure than a surgical one within one month follows.