Immature Sacrococcygeal Teratoma with Microfoci of Yolk Sac Tumor in a Preterm Female Newborn- Is the Surgical Resection Enough?

,Roganovic J,Jonjic N

doi:10.19070/2572-7354-1800019

Abstract

Immature Sacrococcygeal Teratoma with Microfoci of Yolk Sac Tumor in a Preterm Female Newborn- Is the Surgical Resection Enough?

Highlights

Germ cell tumors (GCTs) originate from primordial germ cells with multipotent capacity for differentiation
Prenatal diagnosis is of exceptional importance for the adequate fetal intervention, evaluation of perinatal complications and the selection of the optimal treatment
GCTs are a heterogeneous group of neoplasms broadly divided in two classes: seminomas, consisting of ovarian dysgerminomas and testicular seminomas, and nonseminomas, which include teratomas, embryonal carcinomas, yolk sac tumors, and choriocarcinomas [2]

Summary

Introduction

Germ cell tumors (GCTs) originate from primordial germ cells with multipotent capacity for differentiation. We report a case of a premature female newborn with large sacrococcygeal tumor that was first noticed at birth. A female newborn was delivered vaginally at 29th week of gestation due to premature rupture of membranes. She was the second child from the second pregnancy of a healthy 35-yearold woman. Immature Sacrococcygeal Teratoma with Microfoci of Yolk Sac Tumor in a Preterm Female Newborn- Is the Surgical Resection Enough?. Histology demonstrated grade 3 immature teratoma with microfoci of yolk sac tumor (Figure 3). The child was discharged at the age of 2 months She has been followed-up regularly, and at the age of 3 years she is in complete remission with normal urinary function and bowel movements. Because of the cerebral palsy due to intraventricular hemorrhage, the girl is included in the habilitation program

Findings

Discussion

Conclusion