Abstract
Chronic myelogenous leukemia (CML) is a clonal hematopoietic disorder characterized by the reciprocal translocation involving chromosomes 9 and 22. As a result of this translocation, a novel fusion gene, BCR-ABL is created and the constitutive activity of this tyrosine kinase plays a central role in
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Schedule a callMore From: Clinical cancer research : an official journal of the American Association for Cancer Research
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