Abstract
Irritable bowel syndrome (IBS) and food intolerances have remained a physiologic enigma and diagnostic challenge, largely confirmed by exclusion of other known diseases. Why some individuals experience gastrointestinal (GI) distress when all available clinical testing is normal remains a diagnostic and teleologic challenge. Advances in endoscopic imaging have rapidly progressed from wide field, low-magnification images, to increasingly high magnification (40×–200×), allowing improved visualization of the macro-architecture of polypoid and flat lesions.
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