Abstract
The development of the brain was studied by MRI in living fetuses of pregnant women (performed because of medical reasons or in volunteers). They were from 21 to 37 weeks of gestation. At 21 weeks, diencephalic condensations were evident. By 25 weeks, high-density areas appeared in the prefrontal, central parietal and temporal cortices. The lentiform nucleus began to separate from the diencephalic mass between 26 and 28 weeks. The caudate nucleus, corpus callosum and septal areas were observed by 28 weeks, where the hippocampus was definitively identified by 29 weeks. By 30 weeks, the fornix was evident. Profuse CSF circulation with genesis of new gyri was noted at that stage. By 37 weeks, the brain of the fetus was much the same as that of the child except the insula did not show significant gyri.
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