Abstract

1411 ISSN 1750-743X Immunotherapy (2011) 3(12), 1411–1414 10.2217/IMT.11.138 © 2011 Future Medicine Ltd “Macroscopic imaging, exemplified by bioluminescent imaging, PET and MRI has been useful for establishing the trafficking pattern of adoptively transferred chimeric antigen receptor (CAR)+ T cells, their persistence and antitumor activity. Microimaging techniques ... must now be employed to dissect the molecular mechanisms by which CAR-based therapies effectively function...”

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