Abstract
SummarySeizures and epilepsy are fundamentally neuronal circuit phenomena. This article describes the development and application of multiple dynamic imaging techniques that, in combination, facilitate the elucidation of hippocampal circuit function in animal models of epilepsy. This combined approach has significant promise in furthering our understanding of the mechanisms underlying epilepsy. For an expanded treatment of this topic see Jasper’s Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado‐Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at http://www.ncbi.nlm.nih.gov/books).
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