Abstract
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) using double-focusing sector field (LA-ICP-SFMS) or quadrupole-based mass spectrometers (LA-ICP-QMS) was employed as powerful imaging (mapping) techniques to produce images of detailed regionally specific element distributions in thin tissue sections of different sizes such as control rat brain tissues or tumor regions to study tumor growing. LA-ICP-QMS was employed to investigate the uptake and the transport of nutrient elements in plant tissues or imaging of metals in proteins separated by native 2D BN-PAGE.
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