Abstract
Background: Magnetic resonance spectroscopy (MRS) is used nowadays with increased specificity to distinguish between malignant and benign breast lesions. Objective: To determine the diagnostic accuracy of MRS in malignant breast lesions. Methodology: Newly diagnosed patients (n=158) having breast lesions diagnosed on ultrasound and mammography were enrolled to conduct the present study at Bahawal Victoria Hospital, Bahawalpur, Pakistan for six months. Enrolled patients were informed and consent was taken. Every patient underwent proton MRS using a 1.5 Tesla MR system. Fast scans in various planes were obtained. Mean ± standard deviation (SD) was given for age, size of the lump, and duration of the disease whereas frequency and percentage were given for benign and malignant breast lesions by SPSS version 26. A significant p-value was ≤0.05. Results: The mean age of patients was 41.27 ± 5.48 years. The diagnosis of malignant breast lesions in 80 (50.63%) patients was shown by MRS whereas histopathology showed malignancy in 83 (52.53%) cases. Conclusion: MRS is an accurate diagnostic modality for malignant breast lesions.
Highlights
Breast cancer affects one in every nine Pakistani women [1]
The diagnosis of malignant breast lesions in 80 (50.63%) patients was shown by Magnetic resonance spectroscopy (MRS) whereas histopathology showed malignancy in 83 (52.53%) cases
Magnetic resonance spectroscopy (MRS) of the breast is carried out as an investigational tool just to make a correct diagnosis of breast malignancies [9,10,11]
Summary
Breast cancer affects one in every nine Pakistani women [1]. Any breast lump raises the suspicion of malignancy among females of any age [1]. Mammography and ultrasonography are commonly used modalities for detecting breast cancer nowadays [5,6] They have limitations in diagnosing early malignant lesions. There is an elevated incidence of breast cancer among the female population but the data available is limited regarding the diagnosed malignant breast lesions, so we conducted the study to assess the accuracy of MRS as a diagnostic modality in breast cancer. It is relatively cheap, safe, and noninvasive as compared to histopathology which is reliable but invasive. Magnetic resonance spectroscopy (MRS) is used nowadays with increased specificity to distinguish between malignant and benign breast lesions
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