Abstract

Hemophagocytic lymphohistiocytosis (HLH) and Epstein-Barr virus myelitis may manifest with CNS symptoms. Given the similar clinical neurologic presentations of both conditions, differentiating Epstein-Barr virus myelitis from CNS HLH may prove difficult in a patient with a history of HLH. Herein we report a case of Epstein-Barr virus myelitis treated with intrathecal rituximab in a patient with a history of HLH in remission and highlight the role of radiographic imaging in the proper diagnosis.

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