Imaging Analysis and Immunophenotype Study of Head Neck and Chest Extramedullary Plasmacytoma

Abstract

Extramedullar plasmacytoma refers to the primary plasmacytoma (plasmacytoma is a group of diseases, including multiple myeloma, solitary plasmacytoma and extramedullary plasmacytoma), which is a rare soft tissue malignant tumor composed of plasmacytes, accounting for about 4% of all plasmacytomas. The imaging data of 6 cases of extramedullary plasmacytoma confirmed by pathology were analyzed retrospectively. Results among the 6 cases, the mass was located in the oropharynx in 1 case, in the nasal cavity in 2 cases, in the lung in 2 cases, and in the mediastinum in 1 case. CT revealed a soft, clear boundary, multiple density, and contrast scans from medium to medium. MRI showed that the T1 signal was equal or slightly longer, indicating that the T2 signal was equal or slightly longer, and the diffusion of DWI images was clearly limited and the signal separation was low in some lesions. Tumor necrosis was not evident, and enhanced enhancement was observed in contrast enhanced scanning. In other words, there is a specific image characteristic in extramedullary plasmacytoma, but because of its specificity, diagnostic biopsy is necessary for diagnosis. Preoperative CT and MRI examinations can remove lesions, adjacent tissues, and lymph node lesions. This is very important for early diagnosis, treatment and efficacy evaluation of the disease.