Abstract
Imaging remains the foundation for any radiotherapy (RT). In this article, we will briefly review the rationale of multimodality imaging for target volume definition in RT treatment planning and outline the development of novel RT strategies using new sophisticated RT planning techniques that aim to improve the therapeutic ratio of RT. We will address the current limitations using morphological imaging methods for radical RT. We will review the use of functional imaging to provide biological information that may permit the design of biological based targets that may address the issues of radioresistance such hypoxia and accelerated tumour repopulation as well as the current applications for these methods and their limitations for its utilisation in current RT programmes.
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