Abstract
Neuroblastoma is the most common extracranial neoplasm in children. This disease has a great heterogenity in his presentation and prognosis. 123I-MIBG remains currently a key and reference exam for diagnosis, initial staging, prognosis and follow-up of neuroblastoma. SPECT/CT increased the diagnostic certainty of 123I-MIBG scintigraphy interpretation and help to reduce false negative and false positive results. Bone scan is yet not indicated. 18FDG-PET/CT is not superior to 123I-MIBG in stages 3 and 4. 18FDG-PET/CT is recommended in case of non-avid 123I-MIBG neuroblastoma. 18F-FDOPA PET/CT could represent an alternative exam to 123I-MIBG scintigraphy because of better spatial resolution and no interference with therapy. Other PET radiopharmaceuticals as 124I-MIBG or 18F-MFBG could be interesting and particularly 68Ga-peptides PET/CT as a theranostic agent in providing valuable information for pretherapeutic staging of neuroblastoma.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
