Abstract
BackgroundMultifocal choroiditis (MFC) is multi-inflammatory lesions that occur in the retinal pigment epithelium (RPE) and the choriocapillaris. Optical examinations are the major diagnostic methods to diagnose the disease.ObjectiveTo examine patients with different types of MFC by multiple imageological methods. To summarize the imageology features of different types of MFC to make a medical examination guideline for clinician practices.MethodAll of the patients who included in the study received examinations of fundus color photography, infrared fundus photography, fundus auto fluorescence (FAF), fluorescein fundus angiography (FFA), and optical coherence tomography (OCT), respectively. Finally, imageology features of different types of multifocal choroiditis were summarized.ResultsA total of 51 eyes from 28 patients with diagnosed MFC were included in the study. These patients consisted of 10 males and 18 females aged from 31 to 49 (mean age: 41.5 ± 0.8). 23 patients had MFC on both eye whilst 5 had monocular disease. The MFC lesions were classified as active inflammatory lesions, inactive inflammatory lesions, inflammatory lesions secondary active choroidal neovascularization (CNV) and inflammatory lesions secondary inactive CNV according to literature reports and comprehensive fundus imaging examinations.ConclusionExaminations via fundus color photography, infrared fundus photography, FAF, FFA and OCT indicate typical imageological signals of different types of MFC. These imageology tests can greatly assist the clinicians to identify the MFC and provide proper therapies.
Highlights
Multifocal choroiditis (MFC) is multi-inflammatory lesions that occur in the retinal pigment epithelium (RPE) and the choriocapillaris
The MFC lesions were classified as active inflammatory lesions, inactive inflammatory lesions, inflammatory lesions secondary active choroidal neovascularization (CNV) and inflammatory lesions secondary inactive CNV according to literature reports and comprehensive fundus imaging examinations
Multifocal choroiditis (MFC) is an inflammatory disorder characterized by uveitis and multiple lesion that occurs in the retinal pigment epithelium (RPE) and the choroidal capillary layer [1]
Summary
Multifocal choroiditis (MFC) is multi-inflammatory lesions that occur in the retinal pigment epithelium (RPE) and the choriocapillaris. Optical examinations are the major diagnostic methods to diagnose the disease. Multifocal choroiditis (MFC) is an inflammatory disorder characterized by uveitis and multiple lesion that occurs in the retinal pigment epithelium (RPE) and the choroidal capillary layer [1]. Symptoms of MFC include blurry vision with or without sensitivity to light. Some patients suffer from floaters, blind spots and mild eye discomfort [1, 2]. MFC occurs spontaneously and the cause is currently not known. Current treatment to MFC includes periocular or systemic corticosteroids application [5]. These treatments are managed to alleviate the symptoms, but not offering a permanent cure
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