Abstract
The use of optical technology in guiding surgical intervention is at its earliest stages at the moment. The potential is to facilitate tumour-specific targeting which can potentially result in margin-free tumour and improved survival. In a case study, we investigated the role of optical coherence tomography (OCT) in lesion (squamous cell carcinoma) mapping, assisting the surgeon to correctly deliver photodynamic therapy (PDT) and monitor the outcome. OCT was successful in achieving this, obviating many of the previous shortcomings of PDT follow-up and monitoring process. We also propose the development of OCT-guided fine needle aspiration cytology (FNAC) for more accurate monitoring and mapping.
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