Abstract

Antibody production in mammals in response to a variety of antigens has been extensively investigated. An early appearance of IgM antibodies was usually followed by IgG antibodies (Bauer, Mathies and Stavitsky, 1963). The activity of IgM antibodies was destroyed by treatment with 0·1 M 2‐mercaptoethanol (ME) (Deutsch and Morton, 1957), whilst the titre of IgG antibodies was not diminished. In the fowl a similar pattern of antibody response has been described (Uhr, Finkelstein and Franklin. 1962; Benedict. Brown and Hirsch, 1963; Drecsman, Larson, Pinckard, Groydon and Benedict, 1965). Rosenquist and Gilden (1963), however, found no IgM antibodies in fowl serum in response to bovine serum albumin (BSA) and the antibody titre in the IgG fraction was destroyed by incubation with ME.The results presented in this communication are concerned with (1) the susceptibility of fowl IgG antibodies to ME treatment; and (2) the production of IgM antibodies by the fowl.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.