Abstract
Introduction: Immunoglobulin A vasculitis (formerly known as Henoch Schonlein Purpura) is the most common pediatric vasculitis, which occurs typically at the age of 3-15 years. Mononucleosis, group A Streptococcus, Campylobacter and Mycoplasma are some of the common infectious causes of immunoglobulin A vasculitis. Immunoglobulin A vasculitis is a clinically diagnosed disease. Most common clinical features include nonthrombocytopenic nonpruritic palpable purpura, gastrointestinal involvement, arthritis or arthralgia and renal involvement. Biopsy of skin and/or gastrointestinal lesions con rm the diagnosis, although this is not necessary. Immunoglobulin A vasculitis is a self-limiting disease, which resolves spontaneously. Steroids can be used for the treatment of moderate to severe disease and for the prevention of renal complications. Prognosis relies upon various factors among which involvement of kidneys dictates poor prognosis and requires close follow up. Case Presentation: We are presenting a case of immunoglobulin A vasculitis in a 39-year-old German male following in uenza virus infection. The infectious agent that cause immunoglobulin A vasculitis in our patient was In uenza A virus. Biopsy of the skin lesion con rmed the diagnosis of immunoglobulin A vasculitis in our patient. The patient responded to steroids and his skin and GI ndings resolved. Conclusion: Our case report adds to the literature of medicine by describing in uenza virus as a cause of immunoglobulin A vasculitis in young adult patients. Considering immunoglobulin A vasculitis after in uenza and outside of the typical age of 3-15 years, can help to make earlier diagnosis and prevent complications.
Highlights
Immunoglobulin A vasculitis is the most common pediatric vasculitis, which occurs typically at the age of 3-15 years
Mononucleosis, group A Streptococcus, Campylobacter and Mycoplasma are some of the common infectious causes of immunoglobulin A vasculitis
Case Presentation: We are presenting a case of immunoglobulin A vasculitis in a 39-year-old German male following influenza virus infection
Summary
Immunoglobulin A (IgA) vasculitis is a self-limiting, autoimmune, systemic, most commonly pediatric, small vessel vasculitis [1,2,5]. The rash was nonpruritic, non-painful, and purpuric It progressed from his bilateral legs and inner thighs to his abdomen, back, chest, and face. Pathology confirmed the diagnosis of IgA vasculitis Four days later, he returned with severe worsening abdominal pain, progressive rash on his thighs, legs, back, and arms. He returned with severe worsening abdominal pain, progressive rash on his thighs, legs, back, and arms He complained of arthralgia of bilateral knees and elbows. He was referred to emergency room (ER) where he was started on 20 mg prednisone and discharged Six days later, he developed nausea, diarrhea, hematemesis and severe abdominal pain. Patient was started on prednisone 20 mg which was increased to 60 mg on development of severe abdominal pain, hematemesis, nausea, and diarrhea He was prescribed clobetasol for the skin rash.
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