Abstract
To the Editor:— I have read with interest Dr. Carter Smith's report on the use of salyrgan in one patient over a period of three years (The Journal, February 17, p. 532). He states that only one instance of idiosyncrasy to salyrgan has been reported in the literature, that by Andrews in the Lancet , July 18, 1931. I wish to point out that Dr. Bongiorno and I reported a case of sudden death due to salyrgan in a nephrotic child, aged 4, in the Canadian Medical Journal ( 25 :73 [July] 1931). The injection preceding the fatal one caused a chill, fever, a morbilliform rash, anorexia and malaise. Good diuresis was obtained, whereas previous injections failed to provoke a satisfactory response. A week later the sixth and fatal dose was given, causing sudden death, which was anaphylactic in nature.
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