Abstract
Spontaneous premature closure of the human fetal ductus arteriosus is an uncommon event that often results in significant morbidity and mortality. We present a case of a neonate with prenatal previously not detected intrauterine closure of the ductus arteriosus in a 21-year-old ,G3P1A2L1 mother with type 2 consanguinity at 39 weeks of gestation, with previous scans showing placenta previa grade 1 at 21weeks and Doppler study showing pericardial effusion at 36weeks.Caesarean section was performed in view of absent progression of labour. A male newborn weighing 4100gm, required bag and mask and intubation. With an excellent neonatal outcome. Finally we suggest that fetal echo in third trimester & maternal education programs to avoid self-medication and provide training for good diet is necessary.
Highlights
Intrauterine ductus arteriosus closure is a rare occurrence which has not been fully explored
Spontaneous premature closure of the human fetal ductus arteriosus is an uncommon event that often results in significant morbidity and mortality
Recent data based on serial fetal echocardiography suggest that about 50% of all fetuses whose mothers are undergoing indomethacin treatment for preterm labor develop constriction of the ductus arteriosus, with the proportion of ductal constriction after 34 weeks of gestation increasing exponentially[7,8]
Summary
Intrauterine ductus arteriosus closure is a rare occurrence which has not been fully explored. It is well established that indomethacin can cause premature constriction and can lead to closure of the fetal ductus arteriosus[4]. This can lead to serious fetal and neonatal complications including hydrops fetalis, oligohydramnios, hyperbilirubinemia, pulmonary hypertension, necrotizing enterocolitis and intraventricular hemorrhage[5,6]. When his general condition improved, inotropes and ventilation were gradually weaned and stopped on 4 day of his life, he was taken on CPAP followed by cyclical CPAP for 36hrs and gradually on low flow nasal device and off oxygen on 24hours and simultaneously feeds were increased gradually. On regular followups currently baby is developing normally and being active and cheerful
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Medical and Biomedical Studies
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
