Idiopathic multiple tiny serous retinal pigment epithelial detachments: Report of 2 cases and review of the literature

Abstract

Background Bilateral multiple serous retinal pigment epithelial detachments (PEDs) are a very rare entity. Such conditions may be idiopathic or a presentation of some ocular and/or systemic pathologies. We report 2 unique cases of bilateral multiple serous PEDs without any known cause. Additionally, similar cases of multiple serous idiopathic PEDs reported in the literature were reviewed. Case report The patients were middle-age women with no known related ocular and systemic problems. Fundus examination, fluorescein angiography, and optical coherence tomography found innumerable, small, serous, idiopathic PEDs mainly located in the macular area. One woman also had an associated subretinal pigment epithelial hemorrhage in 1 eye, which regressed spontaneously. There are only a few similar cases reported in the literature. Conclusion Idiopathic bilateral, multiple, tiny, serous PEDs in middle-age healthy people are rare entities that may be a variant of central serous choroidopathy in which retinal pigment epithelium is predominantly involved. The visual prognosis seems to be good without any intervention unless complicated by hemorrhages.