IDF21-0644 Hypertension during pregnancy is a risk factor for developing Hyperglycemia – Results of national screening in Bulgaria

Abstract

Background: In our cross-sectional multicenter population-based study in the Bulgarian population (2012) - 2032 people, men / women (20-80 years) the comparison of the strength of the risk factors on diabetes (obesity, hypertension, dyslipidemia) showed that the most powerful risk factor for development of Diabetes is Hypertension – OR-4.585, 95 % CI: 3.002-7.003, p<0.001. Aim: The aim is to study in the Bulgarian population of pregnant women the relationship between Hyperglycemia during pregnancy and Hypertension (AH) before and during pregnancy. Method: In 547 pregnant women, with a mean age of 30.49±5.127 years, a cross-sectional multicenter population-based study was conducted in 84 settlements in Bulgaria. A questionnaire was completed, blood pressure was measured (Guideline of ESC/ESH, 2018); A two-hour, 75 g oral glucose tolerance test (oGTT) was performed. The statistical analysis was performed using standard SPSS 13.0 for Windows. Results: The incidence of Hyperglycemia for the whole group of pregnant women was 14.4% (79/547). Of all pregnant women screened, 2.4% (13/547) developed AH during the current pregnancy. Hyperglycemia was found in 38.5% (5/13) of women with AH versus 13.9% (74/534) of women without AH, p<0.028. There was a significant correlation between Hyperglycemia and AH during the current pregnancy (p<0.01). Discussion: AH during pregnancy is an additional risk factor for developing Hyperglycemia. The proven significant correlation between Hyperglycemia and AH during pregnancy requires oGTT to be recommended during the initial screening of pregnant women to demonstrate any pre-existing glucose tolerance disorders.