Abstract

Background: Diabetic nephropathy (DN) is a severe complication of diabetes, which increases the mortality of people with type 1 diabetes several-fold. Obesity, defined by BMI, has been associated with the risk of macroalbuminuria and end-stage renal disease, as well as increased risk of cardiovascular and all-cause mortality in this population. However, BMI does not reflect the body fat distribution and central obesity has shown an association with microalbuminuria incidence and with the risk of heart failure hospitalization or death in type 1 diabetes.

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