Abstract
Background: Multiple autoantibody testing identifies children with pre-symptomatic type 1 diabetes (T1D) and is able to stratify those at risk over a 10–15-year period. Identifying children at risk reduces the rates of DKA at presentation and allows them to participate in clinical trials for T1D prevention. T1D general population testing programmes have been trialled in the US and Germany and found a pre-symptomatic T1D rate of 0.3%, achieved a reduction in diabetic ketoacidosis rates from 20% to 5%, and were considered acceptable to families.
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