Identifying Very-Low-Risk Patients for Future Myocardial Infarction or Death.

Abstract

High-sensitivity cardiac troponin (hs-cTn) testing has enabled shorter time intervals between serial measurements when assessing patients with possible acute coronary syndrome (ACS) with a single sample strategy proposed for early risk stratification. Specifically, a rapid rule-out for myocardial infarction (MI) is suitable for a pathway if the sensitivity for 30-day cardiac events is ≥99%. At the population level [n=131,095 emergency department (ED) patients], low hs-cTn results alone yielded sensitivities <99%.