Abstract
Access to adequate and quality health care is a worldwide concern. Without proper access to medicine individuals will often suffer diseases that could be treated or prevented with the proper medicine. Proper dosage is also necessary so that patients can recover from the disease as well as stop the production of drug resistant bacteria and parasites. In collaboration with Norte Dame University, a protocol, using High Performance Liquid Chromatography (HPLC), was developed to quantify the amount of Albendazole, a deworming medication, in tablets from locations in Africa to ensure proper dosage. A Spike and Recovery, a secondary verification method, was developed to verify the efficiency of the column and protocol used. Optimization of the Spike and Recovery method was completed and showed that the efficiency of the column was 97 ± 1 %. Using this protocol, multiple samples have been quantified with one sample falling below the advertised dosage.Support or Funding InformationGrow Iowa Values FundThis abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.
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