Abstract

AbstractThe recent availability of human genomic data has driven genome‐wide scans for natural selection with different approaches based on comparative genetics and population genetics. Such studies have provided many candidates for targets of positive selection in the human genome, but the results should be interpreted with caution because of the inevitability of false positives. Here, approaches for identifying positive selection in the human genome are reviewed, and, especially, an up‐to‐date approach based on haplotype variation and linkage disequilibrium is explained in detail.

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