Abstract

We analyzed the serum from COVID-19 patients and vaccinated subjects, and found that the specific IgA titer level could be used to assist COVID-19 diagnosis, especially in China.

Highlights

  • Specialty section: This article was submitted to Vaccines and Molecular Therapeutics, a section of the journal Frontiers in Immunology

  • Positive PCR test for SARS-CoV-2 is the gold standard for confirming COVID-19 infection, but false negatives do occur, at which time the SARS-CoV-2 specific antibody test can be utilized to assist in diagnosis

  • We hypothesize that specific IgA antibodies found in the serum can be employed to help in the detection of COVID-19 infections

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Summary

Introduction

Specialty section: This article was submitted to Vaccines and Molecular Therapeutics, a section of the journal Frontiers in Immunology. Before the mass adoption of vaccines, specific IgM antibody titers could be used to indicate a recent infection. We hypothesize that specific IgA antibodies found in the serum can be employed to help in the detection of COVID-19 infections.

Results
Conclusion
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