Abstract
Bias in clinical research originates when any systematic error is introduced into any phase of a study that may lead to untrue results. Bias can occur when the research question is formulated, and during data collection, analyses, interpretation, and/or reporting (including publication bias). Because study results distorted by bias might directly impact patient care and health-care policies, there have been great efforts by the scientific community to avoid the introduction of bias in cancer research. In this chapter we discuss the most frequent types of bias encountered in clinical oncology research, as well as potential solutions to minimize them.
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