Abstract
Identification of whole-genome significant single nucleotide polymorphisms in candidate genes associated with body conformation traits in Chinese Holstein cattle.
Highlights
In higher eukaryotes, impaired ribosome biogenesis and function can result in specific phenotypes, the so-called ribosomopathies.[1]
The GWAS based on the mixed-effect linear regression model identified 79 SNPs with genome-wide significant (P < 0.05) association effects on 14 body conformation traits (Table 1, Table S3)
We found six single SNPs that were associated with multiple body conformation traits of dairy cow
Summary
The GWAS based on the mixed-effect linear regression model identified 79 SNPs with genome-wide significant (P < 0.05) association effects on 14 body conformation traits (Table 1, Table S3). We found six single SNPs that were associated with multiple body conformation traits of dairy cow The DNA region from 44.6 to 65.4 Mb of chromosome 18 was identified to be associated with four different body conformation traits (AW, FS, mammary system score and RA) of dairy cows (Table 2, Table S3). It was reported previously to affect udder attachment and height.[13,14] BovineHD2200013812 was identified to have genetic effects on RA This SNP was located within the CACNA1D (calcium channel alpha 1D subunit) gene region.
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