Abstract

SummaryTumour necrosis factor was detected both in the blood and peritoneal fluid of 14 horses with various types of gastrointestinal obstruction. In comparison, tumour necrosis factor was not present in these fluids in 6 normal horses and ponies. The median endotoxin concentration was increased in the blood of horses with colic, but the median interleukin‐1 concentration was not altered in the blood and peritoneal fluid of colic cases in comparison with the normal horses and ponies. This preliminary work supports the hypothesis that tumour necrosis factor is involved in the endotoxaemia which is a consequence of severe gastrointestinal obstructions, and that it is a potential target for medical therapy in such cases.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.