Identification of the volatile bioactive compounds by GC-MS analysis from the leaf extracts of Garcinia cambogia and Garcinia Indica

Abstract

Natural compounds originally derived from plants are historically considered a useful source of potential therapeutic agents, and are known to play essential roles in human diseases. The aim of the current study was to investigate the presence of bioactive compounds in hexane and methanol extracts of Garcinia cambogia and G. indica plant leaves. Both plant leaves were collected, shade dried, made into fine powder and extracted with organic solvents using Soxhlet extractor. The extracts were then analysed for the presence of phytochemicals by gas chromatography-mass spectrometry (GC-MS). The mass spectrum of the chromatography was matched with NIST and WILEY libraries. The GC-MS analysis revealed the presence of 11 and 17 bioactive compounds from the hexane and methanol extracts of G. cambogia respectively. Likewise, G. indica showed 14 compounds each from hexane and methanol extracts. The potent medicinal property within the plant extracts is due to the secondary metabolites present in the plant, which are identified by GCMS. The present investigation revealed preliminary information on bioactive components present in G. cambogia and G. indica leaf extracts, which can open a big platform for pharmacological companies to formulate various drugs from Garcinia species.