Abstract

Vocabulary acquisition is major aspect of language learning in children but also in adults, particularly when learning a foreign language. Selective impairment of vocabulary acquisition is observed in patients with auditory-verbal (phonological) short-term memory deficit, while a more general failure of long-term learning of verbal information is observed in amnesia. Anatomical studies in brain damaged patients have not been fully informative, as they fail to indicate the exact localization of the brain regions involved in vocabulary learning. To identify the relevant brain systems, we performed regional cerebral blood flow (rCBF) PET measurements in six normal subjects while they were learning a list of neologisms or a list of common words.

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