Abstract
Telocyte (Tc) is a new type of classic interstitial cells, described by Popescu et al., in the human pancreas. Telocytes are found in several organs, including the human testis. They are long, thin cells , with small cell bodies, a nucleus containing heterochromatin and presence of mitochondria in the periphery, in addition to a scarcely evident nucleolus. They differ from other interstitial cells by their long moniliform cytoplasmic extensions, called telopodes (Tp), and are usually identified through their ultrastructure by transmission electron microscopy (TEM)
Highlights
How to cite this article: Gomes VL, Braz JK, Martins GM, Clebis NK, Oliveira MF, Morais DB, et al Identification of telocytes in dystrophic mice testis. einstein (São Paulo). 2021;19:eAI5737
Telocytes are found in several organs, including the human testis.[2]. They are long, thin cells (Figure 1), with small cell bodies, a nucleus containing heterochromatin and presence of mitochondria in the periphery, in addition to a scarcely evident nucleolus.[3-5]. They differ from other interstitial cells by their long moniliform cytoplasmic extensions, called telopodes (Tp) (Figure 2), and are usually identified through their ultrastructure by transmission electron microscopy (TEM).(1-5) The long cytoplasmic projections, Tp, comprise thin segments and dilated regions, containing secretory vesicles and mitochondria[4,5] (Figure 2)
Telocytes are located in the peritubular region of the testis and contact myoid cells through cell junctions, while contacting blood vessels and androgenproducing interstitial cells (Leydig cells) through Tp.[2,3,5,6] it is believed that Tc establish homo- and heterocellular junctions, vesicle release and paracrine and/or autocrine signaling
Summary
How to cite this article: Gomes VL, Braz JK, Martins GM, Clebis NK, Oliveira MF, Morais DB, et al Identification of telocytes in dystrophic mice testis. einstein (São Paulo). 2021;19:eAI5737. 3 Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil.
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