Abstract
A molecule called hemoglobin is found in red blood cells that holds oxygen all over the body. Hemoglobin is elastic, round, and stable in a healthy human. This makes it possible to float across red blood cells. But the composition of hemoglobin is unhealthy if you have sickle cell disease. It refers to compact and bent red blood cells. The odd cells obstruct the flow of blood. It is dangerous and can result in severe discomfort, organ damage, heart strokes, and other symptoms. The human life expectancy can be shortened as well. The early identification of sickle calls will help people recognize signs that can assist antibiotics, supplements, blood transfusion, pain-relieving medications, and treatments etc. The manual assessment, diagnosis, and cell count are time consuming process and may result in misclassification and count since millions of red blood cells are in one spell. When utilizing data mining techniques such as the multilayer perceptron classifier algorithm, sickle cells can be effectively detected with high precision in the human body. The proposed approach tackles the limitations of manual research by implementing a powerful and efficient MLP (Multi-Layer Perceptron) classification algorithm that distinguishes Sickle Cell Anemia (SCA) into three classes: Normal (N), Sickle Cells(S) and Thalassemia (T) in red blood cells. This paper also presents the precision degree of the MLP classifier algorithm with other popular mining and machine learning algorithms on the dataset obtained from the Thalassemia and Sickle Cell Society (TSCS) located in Rajendra Nagar, Hyderabad, Telangana, India. Doi: 10.28991/esj-2021-01270 Full Text: PDF
Highlights
Natural blood passes in a tiny circular form that brings oxygen to organs from parts of the human body that are spherical and have a lifespan of around 120 days which produces a new blood cell every 120 days [1]
Metrics assessment techniques [24] are defined as below fig-4: a confusion matrix is a table that reports the counts of true positive, false positive, true negatives and false negatives which are defined as:
Sickle cell anemia is a hematological condition, it was historically one of the peculiar traits of the indigenous community, but it extends to the entire world and requires emergency treatment
Summary
Natural blood passes in a tiny circular form that brings oxygen to organs from parts of the human body that are spherical and have a lifespan of around 120 days which produces a new blood cell every 120 days [1]. Sickle cell anemia is a particular form of irregular blood disorder that causes natural hemoglobin in the red blood cells to change its shape. Sickle cell form is Sticky and hard Disc form, which allows the blood supply to cease in the human body [2]. If one organ is gradually damaged it can spread across the body, which may contribute to death. To escape this kind of illness, early treatment is needed to stop severe problems (Blood Transfusion). A person develops hemoglobin S, which is triggered by two defective genes
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