Abstract
Antioxidants have an important role in delaying the oxidation process and preventing the occurrence of degenerative diseases in the body. Antioxidants consist of synthetic and natural; the use of synthetic antioxidants in a relatively long period is hazardous so that the use of natural antioxidants is considered more potential and safe for the body. The process of extracting secondary metabolites from the leaves of bangun-bangun (Coleus amboinicus L.) is carried out by the maceration method with methanol, then partitioned in stages with n-hexane, chloroform, and ethyl acetate. This research intends to identify secondary metabolites and test antioxidant activity from the ethyl acetate fraction with the DPPH method. Phytochemical screening results of ethyl acetate fraction showed the different secondary metabolite groups such as alkaloids, phenolics & polyphenols, flavonoids, coumarin, and triterpenoids. Antioxidant activity (IC50) obtained is 64.97 with a healthy category, so that the potential to be used as a natural antioxidant.
Highlights
Diterpenoid, triterpenoid, sesquiterpenoid, Antioxidants have an essential part phenolic, flavonoid, alcohol, and aldehyde in delaying the process of oxidation in esters (Arumugam et al, 2016; Riyanto et food and preventing degenerative diseases al, 2020). which has antioxidant activity, for health caused by free radicals (Rani, diarrhea, flatulence, constipation, cough 2017; Akbarirad et al, 2015). medicine, chronic asthma, bronchitis, Neurodegenerative diseases caused liver-kidney, antibacterial malaria, include coronary heart disease, stroke, cytotoxic, anti-inflammatory, anti-diabetic, diabetes, and cancer
Influence of free radicals requires an Preparation of samples Coleus antioxidant
The viscous ethyl acetate extract was continued to phytochemical screening and testing its antioxidant activity
Summary
Diterpenoid, triterpenoid, sesquiterpenoid, Antioxidants have an essential part phenolic, flavonoid, alcohol, and aldehyde in delaying the process of oxidation in esters (Arumugam et al, 2016; Riyanto et food and preventing degenerative diseases al, 2020). which has antioxidant activity, for health caused by free radicals Diterpenoid, triterpenoid, sesquiterpenoid, Antioxidants have an essential part phenolic, flavonoid, alcohol, and aldehyde in delaying the process of oxidation in esters (Arumugam et al, 2016; Riyanto et food and preventing degenerative diseases al, 2020). Which has antioxidant activity, for health caused by free radicals Medicine, chronic asthma, bronchitis, Neurodegenerative diseases caused liver-kidney, antibacterial malaria, include coronary heart disease, stroke, cytotoxic, anti-inflammatory, anti-diabetic, diabetes, and cancer The free radicals are unstable breast milk production (laktogogue) and atomic/molecular species because they hepatoprotective (Damanik et al, 2017). Have one or more unpaired electrons (Mbah et al, 2019). Influence of free radicals requires an Preparation of samples Coleus antioxidant.
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