Abstract
The bovine haemal nodes are lymphatic organs located in the haemal circulation. Their parenchyma is represented by plasma cells, macrophages and B and T lymphocytes. The T helper type 2 (Th2) CD4 lymphocyte can be found within the T lymphocytes. The activated Th2 CD4 lymphocyte produces interleukin-4 (IL-4), a peptidic hormone involved in the acute-phase immune response. This interleukin can promote either B-lymphocyte differentiation and T-lymphocyte proliferation or it can promote the type of immunoglobulin that can be liberated. Our results have shown, by immunostaining with anti-IL-4, not only the presence and localization of these lymphocytes in bovine haemal nodes but also the participation of polymorphonuclear cells (neutrophils) in the storage of IL-4. These results give value to the humoral and cellular immunological importance of haemal nodes in bovines and they can serve as a contribution to determine the cross-reactivity of bovine IL-4 with the human anti-serum used in this work.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
