Abstract
Oxidized LDL (OxLDL) plays an important role in initiation and progression of atherosclerosis. The atherogenicity of OxLDL has been largely attributed to the pool of bioactive lipids generated during LDL oxidation. Very little is known of the effects of LDL oxidation on the phosphatidylinositol (PI) molecules present in LDL, even though it represents close to 8% of total LDL phospholipid pool. The aim of this study was to identify and quantitate oxidized phosphatidylinositol (OxPI) species in OxLDL.
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