Abstract

Improvements in therapeutic management of breast cancer are not distributed evenly across socioeconomic groups. African American women with breast cancer have greater risk of recurrence, shorter overall survival, and survival after relapse, worse toxicity, and worse cosmetic outcome when compared to White women. In the hope of explaining some of these differences and with the fact that protein expression may differ by race and ethnicity, we investigated changes in plasma protein and metabolite expression as a result of radiation in a longitudinal study of women treated with adjuvant whole breast radiation therapy.

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