Abstract
MYH11 and PF4V1 are genes encoding for molecules related to the regulation of angiotensin II (AngII) and angiogenesis, MYH11 induces the synthesis of AngII and PF4V1 inhibits it. An endothelin-angiotensin-atrial natriuretic peptide functional system at the ovarian level is involved in oocyte maturation and ovulation and seems to be controlled by LH. Since most of the protocols used in IVF require the use of gonadotrophins is logical to think on the possible effect of ovarian stimulation on the process related to ovulation and oocyte maturation.
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