Abstract

It is a well-known fact that diabetic retinopathy (DR) is one of the most common causes of visual impairment between the ages of 25 and 74 around the globe. Diabetes is caused by persistently high blood glucose levels, which leads to blood vessel aggravations and vision loss. Early diagnosis can minimise the risk of proliferated diabetic retinopathy, which is the advanced level of this disease, and having higher risk of severe impairment. Therefore, it becomes important to classify DR stages. To this effect, this paper presents a weighted fusion deep learning network (WFDLN) to automatically extract features and classify DR stages from fundus scans. The proposed framework aims to treat the issue of low quality and identify retinopathy symptoms in fundus images. Two channels of fundus images, namely, the contrast-limited adaptive histogram equalization (CLAHE) fundus images and the contrast-enhanced canny edge detection (CECED) fundus images are processed by WFDLN. Fundus-related features of CLAHE images are extracted by fine-tuned Inception V3, whereas the features of CECED fundus images are extracted using fine-tuned VGG-16. Both channels’ outputs are merged in a weighted approach, and softmax classification is used to determine the final recognition result. Experimental results show that the proposed network can identify the DR stages with high accuracy. The proposed method tested on the Messidor dataset reports an accuracy level of 98.5%, sensitivity of 98.9%, and specificity of 98.0%, whereas on the Kaggle dataset, the proposed model reports an accuracy level of 98.0%, sensitivity of 98.7%, and specificity of 97.8%. Compared with other models, our proposed network achieves comparable performance.

Highlights

  • Introduction published maps and institutional affilDiabetes is caused by an accumulation of glucose in the bloodstream [1]

  • We denoted the channel as contrast-limited adaptive histogram equalization (CLAHE)-based for the approach that uses Inception V3 for CLAHE fundus images, and contrast-enhanced canny edge detection (CECED)-based for the approach that uses VGG-16 for CECED fundus images

  • Our article proposed a diabetic retinopathy (DR) identification technique based on weighted fusion capable of processing CLAHE and CECED fundus scans concurrently

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Summary

Introduction

Diabetes is caused by an accumulation of glucose in the bloodstream [1]. Diabetes puts a person at risk for various ailments, such as renal failure, loss of eyesight, teeth bleeding, nerve failure, lower limb seizure, stroke, heart failure, and so on [2]. Diabetic individuals must have comprehensive eye examinations during which the retina has to be examined by an ophthalmologist. Fundus fluorescein angiography, slit lamp biomicroscopy, and fundus imaging are some of the methods used to identify the afflicted eye [4]. In accordance with the survey conducted by the World Health Organization (WHO), diabetes [5] is the seventh most deadly disease. With the supplementary statistics, there has been a high increment of diabetic patients which climbed up to 422 million

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