Abstract

On the basis of chromosomal-banding patterns, karyotypic analysis in 3 cases of chronic myelocytic leukemia (CML) in the blastic phase was performed. The banding pattern was obtained by atebrin staining and the trypsin-saline-Giemsa method. The 3 cases had several characteristics in common: 1. a translocation 9q+; 22q-; 2. an additional chromosome 22q-; 3. an additional chromosome 19, and 4. C-sized marker chromosomes of different morphology and unidentifiable origin.

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