Identification of Antibiotic Resistance of Acinetobacter baumannii in Iraqi Patients

Abstract

A. baumannii is an opportunistic pathogen that was once regarded as a low-category pathogen but is now a prominent source of hospital and community-acquired illnesses. It is a prevalent cause of pneumonia. To investigate the prevalence of antibiotics resistance among A baumannii. Two-hundred clinical smaples were collected including (burns, sputum, urine and wound swabs) from individuals suffering from different complaints such as surgical and wound infections, burns inflammation, inflammation of the urinary tract, pneumonia and COVID-19 patients. 86 A. baumannii bacterial isolates could be picked up from these samples using routine test and VITEK-2 system. After diagnosis the A baumannii strains were subjected to an antibiotic sensitivity test using Kirby-Bauer disk diffusion method against Seven type of antibiotics. A baumannii isolates a exhibited high resistance rate under the effect of tetracycline, Ciprofloxacin, Meropenem and Amikacin antibiotics (92%,76, 72%,72%) respectively. Multidrug resistance profile of 86 A baumannii isolates were 47.6% DR, 37.6% XDR and 15.1 MDR. A significant difference was noticed between the susceptibility profile of 86 A. baumannii isolates at (F.S.P. 50.5, p-value= 0.001). Reduced susceptibility or resistance to carbapenems is increasingly being observed in A. baumannii clinical isolates, which is an opportunistic bacterium associated with serious hospital infections.