Abstract
A new allele of the human leukocyte antigen C (HLA-C) locus was identified during routine HLA typing of a Chinese hematopoietic stem cell donor in Beijing, China. Sequence analysis of exons 2 and 3 of the HLA-C gene revealed the novel polymorphism. The closest matched allele was HLA-Cw*0710. A comparison of the two alleles showed that HLA-Cw*0743 carried a nucleotide substitution of C to A at codon 99 in exon 3, resulting in an amino acid substitution of serine to tyrosine with no obvious change in protein structure.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
