Abstract
One family of Conserved ATPase-containing Domain (CAD) proteins, the SUG1 family, is reported as a regulatory subunit of proteasome and/or a transcriptional mediator. We isolated a cDNA for the Arabidopsis SUG1 gene (AtSUG1), which shares strong homology with members of the SUG1 CAD family. Overproduction of AtSUG1 cDNA weakly restored meiotic division in a fission yeast mutant defective in the mei2 gene, which encodes a meiotic regulator. AtSUG1 was expressed at an almost constitutive level, independent of plant organ or developmental stage. AtSUG1 can functionally substitute for SUG1 in budding yeast.
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