Abstract
Coronavirus disease 2019 (COVID-19) is a multisystem disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), that primarily causes respiratory symptoms. However, an increasing number of cutaneous manifestations associated with this disease have been reported. The aim of this study is to analyze the scientific literature on cutaneous manifestations associated with SARS-CoV-2 by means of a narrative literature review until June 2021. The search was conducted in the following electronic databases: Medline (PubMed), SciELO, and Cochrane Library Plus. The most common cutaneous manifestations in patients with COVID-19 are vesicular eruptions, petechial/purpuric rashes, acral lesions, liveoid lesions, urticarial rash, and maculopapular-erythematous rash. These manifestations may be the first presenting symptoms of SARS-CoV-2 infection, as is the case with acral lesions, vesicular eruptions, and urticaria. In relation to severity, the presence of liveoid lesions may be associated with a more severe course of the disease. Treatment used for dermatological lesions includes therapy with anticoagulants, corticosteroids, and antihistamines. Knowledge of the dermatologic manifestations associated with SARS-CoV-2 contributes to the diagnosis of COVID-19 in patients with skin lesions associated with respiratory symptoms or in asymptomatic patients. In addition, understanding the dermatologic lesions associated with COVID-19 could be useful to establish a personalized care plan.
Highlights
IntroductionCoronaviruses (CoVs) are a large family of zoonotic, single-stranded, enveloped RNA viruses
Published: 24 September 2021Coronaviruses (CoVs) are a large family of zoonotic, single-stranded, enveloped RNA viruses
Analyzed the frequency of skin manifestations associated with SARS-CoV-2 according to case reports/series, and among the types of comorbidities recorded in the studies, obesity, diabetes (7.4%), and hypertension (5.5%) were the most common comorbidities reported in patients with dermatologic lesions associated with COVID-19
Summary
Coronaviruses (CoVs) are a large family of zoonotic, single-stranded, enveloped RNA viruses. CoVs can mutate and recombine rapidly, leading to new CoVs. Coronavirus disease 2019 (COVID-19) is a multisystem disease caused by Severe Acute Respiratory. Syndrome 2 (SARS-CoV-2), which primarily causes respiratory symptoms [1]. The world continues to suffer from the COVID-19 pandemic. Its transmission probability has been estimated at the onset of the pandemic at 1.4–2.5 [2] resulting in at least. 203,391,279 cases of COVID-19 illness and 4,303,090 deaths have been reported. These numbers continue to rise despite the administration of 4,454,162,834 doses of vaccine administered [3]
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